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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPB41L4B
All Species:
11.21
Human Site:
S419
Identified Species:
20.56
UniProt:
Q9H329
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H329
NP_060894.2
900
99712
S419
K
P
S
K
R
Y
P
S
R
R
H
S
T
F
K
Chimpanzee
Pan troglodytes
XP_520178
925
103214
S444
K
P
S
K
R
Y
P
S
R
R
H
S
T
F
K
Rhesus Macaque
Macaca mulatta
XP_001102639
820
92159
P362
Q
L
C
S
K
T
N
P
E
V
H
N
Y
Q
P
Dog
Lupus familis
XP_532028
914
101864
K455
T
F
E
R
K
P
S
K
R
Y
P
S
R
R
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMC8
527
59559
G69
G
G
G
P
L
L
T
G
G
A
A
V
H
I
S
Rat
Rattus norvegicus
B2RYE5
527
59553
G69
G
G
G
P
L
L
T
G
G
A
A
V
H
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509941
820
90648
N362
P
V
L
V
E
I
E
N
L
P
R
S
P
G
A
Chicken
Gallus gallus
XP_419046
839
94372
T374
Y
P
S
R
R
H
S
T
F
K
A
N
N
P
V
Frog
Xenopus laevis
NP_001080234
498
57093
R40
I
P
A
A
G
D
T
R
S
I
I
T
C
R
V
Zebra Danio
Brachydanio rerio
O57457
619
70690
S161
K
H
T
A
G
Y
V
S
E
Y
R
F
V
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650291
972
105216
S392
R
P
S
Q
R
F
A
S
R
Q
S
H
L
L
R
Honey Bee
Apis mellifera
XP_623974
809
90976
G351
L
F
F
W
P
K
I
G
R
L
D
F
K
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788387
843
92835
A377
F
S
R
R
P
S
Y
A
K
K
K
A
A
E
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88
89.1
84.5
N.A.
54.6
54.6
N.A.
35.2
67.1
36.4
25.4
N.A.
33.9
35.3
N.A.
34.6
Protein Similarity:
100
89.8
90
86.9
N.A.
56.6
56.8
N.A.
47.7
75.3
45.4
40.7
N.A.
49.2
52
N.A.
50.1
P-Site Identity:
100
100
6.6
13.3
N.A.
0
0
N.A.
6.6
20
6.6
20
N.A.
33.3
13.3
N.A.
0
P-Site Similarity:
100
100
26.6
26.6
N.A.
0
0
N.A.
13.3
53.3
20
26.6
N.A.
66.6
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
16
0
0
8
8
0
16
24
8
8
0
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
8
% D
% Glu:
0
0
8
0
8
0
8
0
16
0
0
0
0
8
0
% E
% Phe:
8
16
8
0
0
8
0
0
8
0
0
16
0
16
0
% F
% Gly:
16
16
16
0
16
0
0
24
16
0
0
0
0
8
0
% G
% His:
0
8
0
0
0
8
0
0
0
0
24
8
16
0
8
% H
% Ile:
8
0
0
0
0
8
8
0
0
8
8
0
0
16
0
% I
% Lys:
24
0
0
16
16
8
0
8
8
16
8
0
8
8
24
% K
% Leu:
8
8
8
0
16
16
0
0
8
8
0
0
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
8
8
0
0
0
16
8
0
0
% N
% Pro:
8
39
0
16
16
8
16
8
0
8
8
0
8
16
8
% P
% Gln:
8
0
0
8
0
0
0
0
0
8
0
0
0
8
0
% Q
% Arg:
8
0
8
24
31
0
0
8
39
16
16
0
8
16
8
% R
% Ser:
0
8
31
8
0
8
16
31
8
0
8
31
0
0
16
% S
% Thr:
8
0
8
0
0
8
24
8
0
0
0
8
16
0
0
% T
% Val:
0
8
0
8
0
0
8
0
0
8
0
16
8
0
16
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
24
8
0
0
16
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _